posted on 2023-08-11, 14:20authored byJacqueline L.E. Tearle, Satya N.V. Arjunan, Szun S. Tay, Feyza Colakoglu, James Cremasco, Matteo Golo, Maté Biro
Supplementary Video 1B shows representative images of a naltrindole-treated spheroid. Scale bar: 200 µm, number at top left: days post-implantation.
Funding
EMBL Australia (EMBL-Australia)
Cancer Institute NSW (Cancer Institute New South Wales)
Cure Cancer Australia Foundation (CCAF)
History
ARTICLE ABSTRACT
This work describes a readily implementable method that allows for the isolation of individual live tumor cells of interest for downstream analyses, and provides the single-cell transcriptomes of melanoma cells at distinct invasive states, both of which open avenues for in-depth investigations into the transcriptional regulation of the earliest phases of metastasis.