Download Supplementary Movie File from Toward Molecular Imaging–Driven Drug Development in Oncology

<p>Format: .mp4; Size: 59 MB.</p><p><b>Description of Movie</b></p><p> Many rapidly dividing tumor cells express or overexpress surface receptor molecules that can be targeted with antibodies. Tracers (for example, the radionuclide zirconium-89) can be attached to these antibodies and administered to patients. Once the antibody reaches the surface receptor on the tumor cell, it is internalized and digested in an endosome, releasing the tracer. Accumulation of the tracer in the tumor cells can then be visualized.</p><p>NOTE: There is no audio component associated with this video file.</p>