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Table ST1 from Plexin-B1 Mutation Drives Metastasis in Prostate Cancer Mouse Models

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posted on 2023-04-04, 02:22 authored by Boris Shorning, Neil Trent, David F. Griffiths, Thomas Worzfeld, Stefan Offermanns, Matthew J. Smalley, Magali Williamson

Summary of age of mice and weight of primary tumours

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prostate cancer research (charity no. 1156027)

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ARTICLE ABSTRACT

Few therapeutic targets have been identified specifically for preventing locally invasive/oligometastatic prostate cancer from becoming more widely disseminated. Our findings suggest Plexin-B1 signaling, particularly from the clinically relevant P1597L mutant, is such a target.

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    Cancer Research Communications

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    Keywords

    Oncogenes & Tumor SuppressorsSuppressors of metastasisProgression, Invasion & MetastasisMetastasisGenitourinary CancersProstate cancerPreclinical ModelsAnimal models of cancer

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