Table S3 from PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

Doro Pereira, Luiza; Wielgos-Bonvallet, Monica; Misirlioglu, Selim; Khodadai-Jamayran, Alireza; Jelinic, Petar; Levine, Douglas A.

doi:10.1158/2767-9764.28443121

Table S3 from PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

https://doi.org/10.1158/2767-9764.28443121

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posted on 2025-02-19, 08:40 authored by Luiza Doro Pereira, Monica Wielgos-Bonvallet, Selim Misirlioglu, Alireza Khodadai-Jamayran, Petar Jelinic, Douglas A. Levine

<p>Supplementary Table 3 shows enriched gene sets upregulated in OVCAR3 cells treated with veliparib .</p>

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DOI - Is supplement to PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

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This work highlights how different PARPis, especially talazoparib, modulate immune-related gene expression in ovarian cancer cells, independent of the cGAS-STING pathway. These findings may improve our understanding of how different PARPis affect the immune system in various genetic backgrounds.

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Dna Damage And Repair Gene amplification Oncogenes & Tumor Suppressors BRCA family Ovarian Cancer Small Molecule Agents

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Table S3 from PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

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