Table S1 from Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

Okano, Fumiyoshi; Saito, Takanori; Minamida, Yoshitaka; Kobayashi, Shinichi; Ido, Takayoshi; Miyauchi, Yasushi; Wasai, Ukei; Akazawa, Daisuke; Kume, Masahiko; Ishibashi, Masaki; Jiang, Ke; Aicher, Alexandra; Heeschen, Christopher; Yonehara, Tetsu

doi:10.1158/2767-9764.22651579.v1

Table S1 from Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

https://doi.org/10.1158/2767-9764.22651579

journal contribution

posted on 2023-04-18, 13:20 authored by Fumiyoshi Okano, Takanori Saito, Yoshitaka Minamida, Shinichi Kobayashi, Takayoshi Ido, Yasushi Miyauchi, Ukei Wasai, Daisuke Akazawa, Masahiko Kume, Masaki Ishibashi, Ke Jiang, Alexandra Aicher, Christopher Heeschen, Tetsu Yonehara

<p>Clinical, pathological findings in the toxicity study in Cynomolgus Monkeys</p>

Funding

Toray Industries (Toray Industries, Inc.)

History

Related Materials

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DOI - Is supplement to Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

ARTICLE ABSTRACT

Antibody-based cancer therapies have been demonstrated to be effective, but are only approved for a limited number of targets, because the majority of these markers is shared with healthy tissue, which may result in adverse effects. Here, we have successfully identified CAPRIN-1 as a novel truly cancer-specific target, universally expressed on membranes of various cancer cells including cancer stem cells. Clinical studies are underway for the anti-CAPRIN-1 therapeutic antibody TRK-950.