Supplementary Tables S1-S3 from TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies
journal contribution
posted on 2023-04-04, 01:24 authored by Elizabeth Carideo Cunniff, Yosuke Sato, Doanh Mai, Vicky A. Appleman, Shinji Iwasaki, Vihren Kolev, Atsushi Matsuda, Judy Shi, Michiyo Mochizuki, Masato Yoshikawa, Jian Huang, Luhua Shen, Satyajeet Haridas, Vaishali Shinde, Chris Gemski, Emily R. Roberts, Omid Ghasemi, Hojjat Bazzazi, Saurabh Menon, Tary Traore, Pu Shi, Tennille D. Thelen, Joseph Conlon, Adnan O. Abu-Yousif, Christopher Arendt, Michael H. Shaw, Masanori OkaniwaSupplementary tables: Supplementary Table 1 describes where cells were obtained from and details of authentication and mycoplasma testing dates. Supplementary Table 2 shows TAK-676 potency in cynomolgus monkey, human, mouse, and rat STING via time-resolved fluorescence resonance energy transfer assay. Supplementary Table 3 shows pharmacokinetic parameters (Cmax and AUC) after TAK-676 administration in BALB/C mice (A20 tumors).
