Supplementary Tables S1-S2 from Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology

Pourmaleki, Maryam; Socci, Nicholas D.; Hollmann, Travis J.; Mellinghoff, Ingo K.

doi:10.1158/2159-8290.22546798.v1

Supplementary Tables S1-S2 from Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology

journal contribution

posted on 2023-04-04, 02:21 authored by Maryam Pourmaleki, Nicholas D. Socci, Travis J. Hollmann, Ingo K. Mellinghoff

Supplementary Table S1: Overview of multiplexed antibody-based imaging technologies.Supplementary Table S2: Application of multiplexed antibody-based imaging in cancer research.

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ARTICLE ABSTRACT

The shift in cancer therapy from broadly cytotoxic agents toward “personalized” treatments that target specific alterations in each patient's tumor requires diagnostic pathology approaches that are quantitative and biospecimen-friendly. Novel multiplexed antibody-based imaging technologies can measure single-cell expression of over 60 proteins in intact tumor sections and hold promise for clinical oncology.