Supplementary Tables 1 - 10 from microRNA Expression Profiles Identify Subtypes of Mantle Cell Lymphoma with Different Clinicobiological Characteristics

PDF file - 364K, Supplementary Table 1. Comparison of main features of MCL patients from the different studied series; Supplementary Table 2. Normalized expression in miRs with SD variation higher than 50th percentile and detectable expression >25% of cases; Supplementary Table 3a. Subgroups of leukemic MCL according IGHV status and core miR expression clusters and related data; Supplementary Table 3b. Additional data in leukemic MCL with studied mRNA by arrays; Supplementary Table 4a. Results of supervised Limma analysis between Unmutated vs Mutated IGHV MCL; Supplementary Table 4b. Results of supervised Limma analysis between High vs Low SOX11 expressing MCL; Supplementary Table 5a. Overlapping of miR lists from Venn diagram (Supplementary Figure 2); Supplementary Table 5b. Results of supervised Limma analysis between the different MCL subgroups; Supplementary Table 6a. miR expression fold changes for IGHV mutational status in the 16 MCL series compared to the whole sample set; Supplementary Table 6b. Expression fold changes between IGHV mutational status categories in the 16 MCL series for those genes predicted to be targets for IGHV-related miRs and involved in significant enriched pathways; Supplementary Table 7a. MAGIA output for inverse Spearman correlation between IGHV-related miRs and mRNA expression values in 16 leukemic MCL; Supplementary Table 7b. Significant results from GSEA analysis from pre-ranked list of correlations between IGHV-related miRs and their putative targets; Supplementary Table 7c. Gene lists from significant GSEA analysis results from pre-ranked list of correlations between IGHV-related miRs and their putative targets; Supplementary Table 8a. MAGIA output for inverse Spearman correlation between miR-708 and miR-455-5p/3p and mRNA expression values in 16 leukemic MCL; Supplementary Table 8b. Enrichment analysis (g:Profiler) significant results from inversely correlated predicted targets for miR-708 and miR-455-5p/3p (top 75% subset); Supplementary Table 9. Proliferation signature calculations in the 16 leukemic MCL with gene expression data; Supplementary Table 10. Correlation analysis of miR expression and MCL proliferation signature.