Supplementary Tables 1-6 from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
posted on 2023-03-31, 18:13authored byClara Guerzoni, Valentina Fiori, Mario Terracciano, Maria Cristina Manara, Diego Moricoli, Michela Pasello, Marika Sciandra, Giordano Nicoletti, Mara Gellini, Sabrina Dominici, Claudia Chiodoni, Pier Maria Fornasari, Pier-Luigi Lollini, Mario P. Colombo, Piero Picci, Maurizio Cianfriglia, Mauro Magnani, Katia Scotlandi
Supplementary Table S1: Efficacy of anti-CD99 mAb 0662 in a panel of EWS cell lines Supplementary Table S2: Fold induction/reduction of gene expression in treated samples over control mRNAs, analyzed with F-statistic (error <5%). Supplementary Table S3: Fold induction/reduction of protein expression in 5 min treated samples over control Supplementary Table S4: Ratio of firefly and Renilla luciferase signals in Saos-2 p53 deficient cell line co-transfected with a p53-reporter plasmid (pG13-LUC) and pCDNA3.1-E.V., pcDNA3.1-p53WT or mutant pcDNA3.1- p53S241F. Supplementary Table S5: Evaluation of NK number and activity in the four mice groups. Supplementary Table S6: Mice weight and blood parameters of mice from control or treated groups.