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Supplementary Table from Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

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posted on 2023-04-03, 22:01 authored by Parijatham S. Thomas, Anisha B. Patel, J. Jack Lee, Diane D. Liu, Mike Hernandez, Miguel Muzzio, Alejandro Contreras, Valerie Sepeda, Carrie Mays, Diane Weber, Lana A. Vornik, Seema A. Khan, Eileen Dimond, Brandy M. Heckman-Stoddard, Marjorie Perloff, Powel H. Brown
Supplementary Table from Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

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National Cancer Institute (NCI)

United States Department of Health and Human Services

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Duncan Family Institute for Cancer Prevention and Risk Assessment (Duncan Family Institute)

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ARTICLE ABSTRACT

Bexarotene is a rexinoid that has been shown to prevent mammary tumors in mouse models but oral dosing has toxicities. This phase I study evaluates topical bexarotene, as a potential chemoprevention agent, for safety and toxicity in high-risk women for breast cancer.

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    Cancer Prevention Research

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