American Association for Cancer Research

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Supplementary Table ST2 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

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journal contribution
posted on 2023-04-04, 02:20 authored by Shaaron Ochoa-Rios, Calvin R.K. Blaschke, Mengjun Wang, Kendell D. Peterson, Andrew DelaCourt, Stéphane Elie Grauzam, David Lewin, Peggi Angel, Lewis R. Roberts, Richard Drake, Anand S. Mehta

Lists individual N-glycans, ALT (Alanine transaminase), AST (aspartate aminotransferase), ALK (Alkaline phosphatase), and AFP (Alpha-fetoprotein) of analysis to differentiate patients with iCCA from PSC. 1Possible biomarkers 2n: number of total patients 3distribution of iCCA (n=30) and PSC (n=17) patients. 4AUC (Area Under the Curve) 5CI (confidence interval) 6p value. Some iCCA patients were excluded from the analysis due to missing clinical information.


HHS | National Institutes of Health (NIH)



This work elucidates the N-glycan alterations that occur directly in iCCA tissue and utilizes this information to discover serum biomarkers that can be used for the noninvasive detection of iCCA.