Supplementary Table S4 from Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ

O'Shea, Anne E.; Clifton, Guy T.; Qiao, Na; Heckman-Stoddard, Brandy M.; Wojtowicz, Malgorzata; Dimond, Eileen; Bedrosian, Isabelle; Weber, Diane; Garber, Judy E.; Husband, Alexander; Pastorello, Ricardo; Lee, J. Jack; Hernandez, Mike; Liu, Diane D.; Vornik, Lana A.; Brown, Powel H.; Alatrash, Gheath; Peoples, George E.; Mittendorf, Elizabeth A.

doi:10.1158/1940-6207.22806880.v1

Supplementary Table S4 from Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ

journal contribution

posted on 2023-05-11, 23:00 authored by Anne E. O'Shea, Guy T. Clifton, Na Qiao, Brandy M. Heckman-Stoddard, Malgorzata Wojtowicz, Eileen Dimond, Isabelle Bedrosian, Diane Weber, Judy E. Garber, Alexander Husband, Ricardo Pastorello, J. Jack Lee, Mike Hernandez, Diane D. Liu, Lana A. Vornik, Powel H. Brown, Gheath Alatrash, George E. Peoples, Elizabeth A. Mittendorf

Supplementary Table S4: Lymphocyte infiltration

History

ARTICLE ABSTRACT

This trial showed that vaccination of patients with HLA-A2-positive DCIS with NeuVax in the preoperative setting can induce a sustained antigen-specific T-cell response. This provides proof of principle that vaccination in the preoperative or adjuvant setting may stimulate an adaptive immune response that could potentially prevent disease recurrence.