posted on 2023-08-25, 14:20authored byThomas S. Dexheimer, Nathan P. Coussens, Thomas Silvers, John Wright, Joel Morris, James H. Doroshow, Beverly A. Teicher
Table S2. Links to the PubChem assays.
History
ARTICLE ABSTRACT
Clinical efficacy of DNA-damaging anticancer drugs can be influenced by the DNA damage response in tumor cells. The potentiation of DNA-damaging drugs by pharmacologic modulation of DNA repair pathways was assessed in multicellular tumor spheroids. Although most combinations demonstrated additive cytotoxicity, synergistic cytotoxicity was observed for several drug combinations.