American Association for Cancer Research
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Supplementary Table 1 from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star

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journal contribution
posted on 2023-04-03, 18:20 authored by Wangyang Zheng, Daolin Ji, Yongxu Zhou, Liang Yu, Peng Huang, Yuling Zheng, Nanfeng Meng, Hang Wang, Xue Bai, ZiYue Huang, Wangming Chen, Judy W.P. Yam, Yi Xu, Yunfu Cui

Supplementary Table 1: Exosomal ncRNAs involved in cell-to-cell communication in cholangiocarcinoma (CCA)

Funding

National Natural Science Foundation of China

Special Project of China Postdoctoral Science Foundation

China Postdoctoral Science Foundation

Heilongjiang Postdoctoral Science Foundation

Natural Science Foundation of Heilongjiang Province

Postgraduate Innovative Research Project of Harbin Medical University

Foundation of Key Laboratory of Myocardial Ischemia, Ministry of Education

Chen Xiaoping Foundation for the Development of Science and Technology of Hubei Province

The Fundamental Research Funds for the Heilongjiang Provincial Universities

Hong Kong Scholars Program

History

ARTICLE ABSTRACT

Hepatobiliary cancers are a heterogeneous group of malignancies with a dismal prognosis. Despite intensive research efforts focused on these tumors, methods for early diagnosis and effective targeted therapies are still lacking. Exosomes, released by most cells, exist in all kinds of body fluids and play an important role in cell-to-cell communication. They are small membranous vesicles containing biological molecules, such as noncoding RNAs (ncRNA), which are not translated into proteins, but they exert effects on the regulation of gene transcription and translation. There is growing evidence for the essential roles of ncRNAs in exosomes in both physiologic and pathologic conditions of hepatobiliary cancers. They have been identified as sensitive diagnostic biomarkers as well as potential therapeutic targets. The present review discusses recent findings in the cross-talk between hepatobiliary cancers cells and the surrounding cells of the microenvironment and discuss their potential clinical usage.