Supplementary Table 1, Figures 1 - 10 from MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting <i>SOD3</i> and <i>TNF<b>α</b></i>

<p>PDF file, 185K, Supplementary Table S1. Sequences of the primers used in plasmid instruction or in real-time PCR. Supplementary Figure S1. The ROS levels in miR-21 over-expressed cells. Supplementary Figure S2 The ROS levels in 5 Gy-irradiated cells. Supplementary Figure S3 IR could not further increase miR-21 levels in the cells over-expressed with miR-21. Supplementary Figure S4 The SOD levels in miR-21 over-expressed cells at different times after exposure to 5 Gy. Supplementary Figure S5 The sequence of SOD33'UTR contains a potential miR-21 binding site. Supplementary Figure S6 SOD3 activity in the cells over-expressed with SOD3. Supplementary Figure S7 The sequence of TNFa3'UTR contains a potential miR-21 binding site. Supplementary Figure S8 The SOD2 mRNA levels in the cells over-expressed with TNFa. Supplementary Figure S9 SOD activity. Supplementary Figure S10 miR-21 does not affect the levels and activities of catalase and glutathione peroxidase.</p>