Supplementary Figures from Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells

Suppl Fig S1: Levels of Wnt5a expression in brain tumors correlate to aggressiveness or outcome; Suppl Fig S2: Wnt5a overexpression sustains TPCs invasive capability; Suppl Fig S3: Elevated Wnt5a expression promotes migratory capability in otherwise poorly motile U87MG, both in vitro and in vivo; Suppl Fig S4: Pathways enrichment of invasive TPCs progeny based on Wnt5a levels; Suppl Fig S5: Mesenchymal hGBM TPCs are endowed with enhanced dispersal ability to distribute widely in the brain as compared to classical TPCs; Suppl Fig S6: Hypothetical mechanism of Wnt5a regulation that confers the infiltratory phenotype in hGBM TPCs;