Supplementary Figures 1-8 from ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features

<p>PDF file - 432K, Supplementary Figure 1 Histopathological and clinical parameters of primary prostate cancer patients in the two patient cohorts evaluated by TMAs. Supplementary Figure 2 ESE3/EHF knockdown induces epithelial to mesenchymal transition Supplementary Figure 3 Transient downregulation of ESE3/EHF induces a mesenchymal phenotype Supplementary Figure 4 In vivo formation of lung metastasis Supplementary Figure 5 Prostato-sphere formation by prostate epithelial cells Supplementary Figure 6 Transient downregulation of ESE3/EHF in PrECs and RWPE-1 cells induces stem-like properties Supplementary Figure 7 Prostato-sphere formation and stem-like properties in DU145 cells Supplementary Figure 8 Overall survival and PSA biochemical relapse in prostate cancer patients</p>