Supplementary Figures 1-6 from Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
posted on 2023-03-30, 21:35authored byMoo Rim Kang, Glen Yang, Robert F. Place, Klaus Charisse, Hila Epstein-Barash, Muthiah Manoharan, Long-Cheng Li
PDF file - 687K, Figure S1. dsP21-322 triggers changes in cell morphology associated with growth inhibition. Figure S2. Anti-growth activities of LNP-dsP21-322-2'F and its non-formulated derivatives. Figure S3. Duplex stability in water and detection of nucleic acid background signal in urine. Figure S4. Uptake of LNP-formulated dsP21-322-2'F-FITC by bladder urothelium. Figure S5. GFP signature of orthotopic tumors in excised mouse bladders. Figure S6. Muscle invasive bladder tumor and metastatic bladder tumor in the kidney