Supplementary Figure from The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells
Funding
Japan Society for the Promotion of Science (JSPS)
Japan Agency for Medical Research and Development (AMED)
Takeda Science Foundation (TSF)
MSD Life Science Foundation, Public Interest Incorporated Foundation (SD Life Science Foundation)
Daiwa Securities Health Foundation
Nagono Medical Foundation
History
ARTICLE ABSTRACT
This study identifies signaling pathways essential for maintaining the stemness and metastatic potential of colorectal cancer cells and proposes CREB as a therapeutic target in metastatic colorectal cancer.