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Supplementary Figure from The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells

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posted on 2023-03-31, 05:40 authored by Teruaki Fujishita, Yasushi Kojima, Rie Kajino-Sakamoto, Emi Mishiro-Sato, Yasuhiro Shimizu, Waki Hosoda, Rui Yamaguchi, Makoto Mark Taketo, Masahiro Aoki
Supplementary Figure from The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells

Funding

Japan Society for the Promotion of Science (JSPS)

Japan Agency for Medical Research and Development (AMED)

Takeda Science Foundation (TSF)

MSD Life Science Foundation, Public Interest Incorporated Foundation (SD Life Science Foundation)

Daiwa Securities Health Foundation

Nagono Medical Foundation

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ARTICLE ABSTRACT

This study identifies signaling pathways essential for maintaining the stemness and metastatic potential of colorectal cancer cells and proposes CREB as a therapeutic target in metastatic colorectal cancer.

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