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Supplementary Figure SF1 from Mouse IgG2a Isotype Therapeutic Antibodies Elicit Superior Tumor Growth Control Compared with mIgG1 or mIgE

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posted on 2023-04-04, 02:05 authored by Natasa Vukovic, Aina Segués, Shuyu Huang, Martin Waterfall, Alice J.A.M. Sijts, Dietmar M. Zaiss

Quality control of anti-Thy1.1 antibodies.

Funding

EC | Horizon 2020 Framework Programme (H2020)

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ARTICLE ABSTRACT

Direct comparisons of different antibody isotypes of the same specificity in cancer settings are still scarce. Here, it is shown that mIgG2a has a greater effect compared with mIgG1 and mIgE in controlling tumor growth in a therapeutic setting.

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    Cancer Research Communications

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    Keywords

    Tumor MicroenvironmentImmune cells and the microenvironmentImmunotherapyAntibody immunotherapy

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    CC BY

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