American Association for Cancer Research
Browse
crc-22-0117-s06.pdf (221.88 kB)

Supplementary Figure S4 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer

Download (221.88 kB)
journal contribution
posted on 2023-04-04, 01:41 authored by Hao Chen, Gregory M. Cresswell, Sarah Libring, Mitchell G. Ayers, Jinmin Miao, Zhong-Yin Zhang, Luis Solorio, Timothy L. Ratliff, Michael K. Wendt

Corresponding representative dot plots for the quantification in figure 2B-C and additional T cell exhaustion marker analysis in the study of D2.A1 model.

Funding

HHS | NIH | National Cancer Institute (NCI)

Indiana Clinical and Translational Science Institute

American Cancer Society (ACS)

History

ARTICLE ABSTRACT

Findings present inhibition of SHP2 as a therapeutic option to limit breast cancer metastasis by promoting antitumor immunity.