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Supplementary Figure S3 from Immunologic Assessment of Tumors from a Race-matched Military Cohort Identifies Mast Cell Depletion as a Marker of Prostate Cancer Progression

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posted on 2023-08-01, 14:20 authored by Cara C. Schafer, Jiji Jiang, Sally Elsamanoudi, Darryl Nousome, Denise Y. Young, Yingjie Song, Isabell A. Sesterhenn, Gregory T. Chesnut, Shyh-Han Tan

Supplementary Figure S3 shows non-significant relative cell type scores by BCR status.

Funding

DOD | USA | MEDCOM | CDMRP | DOD Prostate Cancer Research Program (PCRP)

DOD | Uniformed Services University of the Health Sciences (USU)

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ARTICLE ABSTRACT

Our findings demonstrate that there are immune-related genes and pathways that differ by race. Impaired intratumoral cellular immune composition, especially for TIL-normalized mast cells, may be vital in predicting and contributing to prostate cancer disease progression.

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    Cancer Research Communications

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    Keywords

    Computational MethodsGene expression profilingTumor MicroenvironmentImmune cells and the microenvironmentImmunologyImmune responses to cancerDescriptive StudiesCancer DisparitiesGenitourinary CancersProstate cancerBiomarkersPrognostic biomarkersTumor HeterogeneitySurvivorship Research

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