Supplementary Figure S2 from Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma

Alpen, Karen; Maclnnis, Robert J.; Vajdic, Claire M.; Lai, John; Dowty, James G.; Koh, Eng-Siew; Hovey, Elizabeth; Harrup, Rosemary; Nguyen, Tuong L.; Li, Shuai; Joseph, David; Benke, Geza; Dugué, Pierre-Antoine; Southey, Melissa C.; Giles, Graham G.; Nowak, Anna K.; Drummond, Katharine J.; Schmidt, Daniel F.; Hopper, John L.; Kapuscinski, Miroslaw K.; Makalic, Enes

doi:10.1158/2767-9764.28728241

Supplementary Figure S2 from Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma

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posted on 2025-04-03, 21:47 authored by Karen Alpen, Robert J. Maclnnis, Claire M. Vajdic, John Lai, James G. Dowty, Eng-Siew Koh, Elizabeth Hovey, Rosemary Harrup, Tuong L. Nguyen, Shuai Li, David Joseph, Geza Benke, Pierre-Antoine Dugué, Melissa C. Southey, Graham G. Giles, Anna K. Nowak, Katharine J. Drummond, Daniel F. Schmidt, John L. Hopper, Miroslaw K. Kapuscinski, Enes Makalic

Supplementary Figure S2 shows the estimation of genetic ancestry of AGOG, GliomaScan and GICC samples by way of scatter plot of PC1 versus PC2.

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ARTICLE ABSTRACT

Further investigation of the potential susceptibility regions identified in our study may lead to a better understanding of glioma genetic risk and the underlying biological etiology of glioma. Our study suggests sex may play a role in genetic susceptibility and highlights the importance of sex-specific analysis in future glioma research.

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Genetics Of Cancer Risk & Outcome CNS Cancers Gliomas, Glioblastomas Epidemiology

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Supplementary Figure S2 from Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma

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