Supplementary Figure S2 from Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma
posted on 2025-04-03, 21:47authored byKaren Alpen, Robert J. Maclnnis, Claire M. Vajdic, John Lai, James G. Dowty, Eng-Siew Koh, Elizabeth Hovey, Rosemary Harrup, Tuong L. Nguyen, Shuai Li, David Joseph, Geza Benke, Pierre-Antoine Dugué, Melissa C. Southey, Graham G. Giles, Anna K. Nowak, Katharine J. Drummond, Daniel F. Schmidt, John L. Hopper, Miroslaw K. Kapuscinski, Enes Makalic
<p>Supplementary Figure S2 shows the estimation of genetic ancestry of AGOG, GliomaScan and GICC samples by way of scatter plot of PC1 versus PC2.</p>
Further investigation of the potential susceptibility regions identified in our study may lead to a better understanding of glioma genetic risk and the underlying biological etiology of glioma. Our study suggests sex may play a role in genetic susceptibility and highlights the importance of sex-specific analysis in future glioma research.