American Association for Cancer Research
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Supplementary Figure FS1 from Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis

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posted on 2023-04-04, 01:41 authored by Lijun Yao, Reyka G. Jayasinghe, Brian H. Lee, Swati S. Bhasin, William Pilcher, Deon Bryant Doxie, Edgar Gonzalez-Kozlova, Surendra Dasari, Mark A. Fiala, Yered Pita-Juarez, Michael Strausbauch, Geoffrey Kelly, Beena E. Thomas, Shaji K. Kumar, Hearn Jay Cho, Emilie Anderson, Michael C. Wendl, Travis Dawson, Darwin D'souza, Stephen T. Oh, Giulia Cheloni, Ying Li, John F. DiPersio, Adeeb H. Rahman, Kavita M. Dhodapkar, Seunghee Kim-Schulze, Ravi Vij, Ioannis S. Vlachos, Shaadi Mehr, Mark Hamilton, Daniel Auclair, Taxiarchis Kourelis, David Avigan, Madhav V. Dhodapkar, Sacha Gnjatic, Manoj K. Bhasin, Li Ding

Expression of cell type markers in CITE-seq and comparison of cell subset abundance between technical replicates and across different centers

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Multiple Myeloma Research Foundation (MMRF)

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ARTICLE ABSTRACT

scRNA-seq, CyTOF, and CITE-seq are increasingly used for evaluating cellular heterogeneity. Understanding their concordances is of great interest. To date, this study is the most comprehensive examination of the measurement of the immune microenvironment in multiple myeloma using the three techniques. Moreover, we identified markers predicted to be significantly associated with multiple myeloma rapid progression.

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