Supplementary Figure 8 from Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics

Tearle, Jacqueline L.E.; Arjunan, Satya N.V.; Tay, Szun S.; Colakoglu, Feyza; Cremasco, James; Golo, Matteo; Biro, Maté

doi:10.1158/2767-9764.23932445.v1

crc-22-0305-s08.pdf (176.74 kB)

Supplementary Figure 8 from Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics

journal contribution

posted on 2023-08-11, 14:20 authored by Jacqueline L.E. Tearle, Satya N.V. Arjunan, Szun S. Tay, Feyza Colakoglu, James Cremasco, Matteo Golo, Maté Biro

Supplementary Figure 8 shows a summary of GSEA pathway analyses using Hallmarks gene set showing top 25 enriched pathways for each comparison

Funding

EMBL Australia (EMBL-Australia)

Cancer Institute NSW (Cancer Institute New South Wales)

Cure Cancer Australia Foundation (CCAF)

History

ARTICLE ABSTRACT

This work describes a readily implementable method that allows for the isolation of individual live tumor cells of interest for downstream analyses, and provides the single-cell transcriptomes of melanoma cells at distinct invasive states, both of which open avenues for in-depth investigations into the transcriptional regulation of the earliest phases of metastasis.