posted on 2023-04-03, 21:03authored byJoan Montero, Jason Stephansky, Tianyu Cai, Gabriel K. Griffin, Lucia Cabal-Hierro, Katsuhiro Togami, Leah J. Hogdal, Ilene Galinsky, Elizabeth A. Morgan, Jon C. Aster, Matthew S. Davids, Nicole R. LeBoeuf, Richard M. Stone, Marina Konopleva, Naveen Pemmaraju, Anthony Letai, Andrew A. Lane
Time and dose-dependent response of primary BPDCN to venetoclax in vitro. (A) Cell death measurement by flow cytometry at 4 and 8 hours after addition of venetoclax at the indicated doses in a primary BPDCN, represented as change in Annexin V positivity relative to vehicle. (B) Dose response of primary BPDCNs and AMLs to venetoclax in vitro measured as in (A).