Supplementary Figure 3 from Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy

Davis, Richard W.; Klampatsa, Astero; Cramer, Gwendolyn M.; Kim, Michele M.; Miller, Joann M.; Yuan, Min; Houser, Cassandra; Snyder, Emma; Putt, Mary; Vinogradov, Sergei A.; Albelda, Steven M.; Cengel, Keith A.; Busch, Theresa M.

doi:10.1158/2767-9764.24119235.v1

Supplementary Figure 3 from Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy

journal contribution

posted on 2023-09-11, 14:20 authored by Richard W. Davis, Astero Klampatsa, Gwendolyn M. Cramer, Michele M. Kim, Joann M. Miller, Min Yuan, Cassandra Houser, Emma Snyder, Mary Putt, Sergei A. Vinogradov, Steven M. Albelda, Keith A. Cengel, Theresa M. Busch

Supplemental Figure 3. Preceding PDT with TI significantly reduces response in male AB12-bearing mice

Funding

HHS | NIH | National Cancer Institute (NCI)

History

ARTICLE ABSTRACT

Although mesothelioma is difficult to treat, we have shown that combining surgery with a form of radiation, photodynamic therapy, may help people with mesothelioma live longer. In this study, we demonstrate in mice that this regimen could be further improved by addressing the inflammation induced as a by-product of surgery.