Supplementary Figure 3 from Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38α Signaling Pathway

PDF file - 309K, The protein phosphorylation spectrum activated by UVA, UVB or SUV irradiation. N/TERT-1 cells were irradiated with UVA (60 kJ/m2), UVB (3.6 kJ/m2) or SUV (60 kJ UVA/m2/3.6 kJ UVB/m2). Protein extracts (500 μg) were used for phospho-kinase protein array analysis. Array spots were visualized by ECL kit. The density of the each duplicated array spot in Figure 3A was measured as described in Materials and Methods. The table shows the fold change in SUV-induced phosphorylation of all 46 kinases and transcription factors compared to untreated control (i.e., value of 1). Data are shown as an average of duplicate samples.