Supplementary Figure 3 from Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells
posted on 2023-04-03, 13:21authored byC. Elizabeth Caldon, C. Marcelo Sergio, Jian Kang, Anita Muthukaruppan, Marijke N. Boersma, Andrew Stone, Jane Barraclough, Christine S. Lee, Michael A. Black, Lance D. Miller, Julia M. Gee, Rob I. Nicholson, Robert L. Sutherland, Cristin G. Print, Elizabeth A. Musgrove
PDF file, 41KB, Supplementary Figure 3: Effect of overexpression of cyclins E1 and E2 on antiestrogen-induced growth arrest. T-47D cells overexpressing cyclin E1, cyclin E2 or vector control were treated with fulvestrant or vehicle. Densitometry of Western blots of cell lysates collected after 24h (A) or 48h (B) fulvestrant treatment. Loading was corrected using β-actin levels. Data represent mean � SEM of quadruplicate experiments.