Supplementary Figure 1. from Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression

McDonald, Malcolm F.; Curry, Rachel Naomi; O’Reilly, Isabella; Lozzi, Brittney; Cervantes, Alexis; Lee, Zhung-Fu; Rosenbaum, Anna; He, Peihao; Mohila, Carrie; Harmanci, Arif O.; Serin Harmanci, Akdes; Deneen, Benjamin; Rao, Ganesh

doi:10.1158/2767-9764.28727392

Supplementary Figure 1. from Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression

https://doi.org/10.1158/2767-9764.28727392

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posted on 2025-04-03, 21:41 authored by Malcolm F. McDonald, Rachel Naomi Curry, Isabella O’Reilly, Brittney Lozzi, Alexis Cervantes, Zhung-Fu Lee, Anna Rosenbaum, Peihao He, Carrie Mohila, Arif O. Harmanci, Akdes Serin Harmanci, Benjamin Deneen, Ganesh Rao

<p>Supplementary Figure 1</p>

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DOI - Is supplement to Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression

ARTICLE ABSTRACT

Immunosuppression in malignant glioma remains a barrier to therapeutic development. CD83 overexpression in human and mouse glioma increases survival. CD83+ tumor cells promote signatures related to cytotoxic T cells, enhanced activation of CD8+ T cells, and increased proinflammatory cytokines. These findings suggest that tumor-expressed CD83 could mediate tumor–immune communications.

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CNS Cancers Gliomas, Glioblastomas Tumor Microenvironment Immune cells and the microenvironment Cytokines and the microenvironment Computational Methods Gene expression profiling Sequence analysis Immunology

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Supplementary Figure 1. from Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression

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