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Supplementary Fig S3 from Fusobacterium nucleatum Load Correlates with KRAS Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma

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posted on 2023-09-27, 19:20 authored by Koki Takeda, Minoru Koi, Yoshiki Okita, Sija Sajibu, Temitope O. Keku, John M. Carethers

Fig S3 shows Kaplan-Meier curves for overall survival in colorectal cancer patients

Funding

HHS | NIH | National Cancer Institute (NCI)

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

UM | Medical School, University of Michigan (U-M Medical School)

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ARTICLE ABSTRACT

The authors demonstrated that Fn is enriched in colorectal cancers exhibiting the SSP phenotype, and in colorectal cancers carrying KRAS mutations. Fn infection should be considered as a candidate risk factor specific to colorectal cancers with the SSP phenotype and with KRAS mutations.

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    Cancer Research Communications

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    Keywords

    Gastrointestinal CancersColorectal cancerOncogenes & Tumor SuppressorsKrasBiomarkersCarcinogen exposure biomarkersTranslational ResearchEnvironmental Risk FactorsMicrobiomeTumor MicroenvironmentMicrobiome and the microenvironment

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