Supplementary Data from Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

Sokač, Mateo; Ahrenfeldt, Johanne; Litchfield, Kevin; Watkins, Thomas B.K.; Knudsen, Michael; Dyrskjøt, Lars; Jakobsen, Martin R.; Birkbak, Nicolai J.

doi:10.1158/2767-9764.22545327.v1

Supplementary Data from Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

https://doi.org/10.1158/2767-9764.22545327

journal contribution

posted on 2023-04-04, 01:43 authored by Mateo Sokač, Johanne Ahrenfeldt, Kevin Litchfield, Thomas B.K. Watkins, Michael Knudsen, Lars Dyrskjøt, Martin R. Jakobsen, Nicolai J. Birkbak

<p>Supplementary data</p>

Funding

Lundbeckfonden (Lundbeck Foundation)

Aarhus Universitets Forskningsfond (Aarhus University Research Foundation)

Danish Cancer Society Research Center (DCRC)

History

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DOI - Is supplement to Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

ARTICLE ABSTRACT

The cGAS-STING pathway is induced by CIN, triggers inflammation and is often deficient in cancer. We provide a tool to evaluate cGAS-STING activity and demonstrate clinical significance in immunotherapy response.