Supplementary Data from CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer

Chen, Xuehan; Liu, Yanzhuo; Wang, Yang; Wang, Chenlong; Chen, Xuewei; Xiong, Yu; Liu, Lilong; Yuan, Xi; Tang, Honglin; Shu, Chong; Zhang, Jing; Guo, Austin M.; Chen, Honglei; Yang, Jing

doi:10.1158/0008-5472.22432832.v1

Supplementary Data from CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer

journal contribution

posted on 2023-03-31, 05:42 authored by Xuehan Chen, Yanzhuo Liu, Yang Wang, Chenlong Wang, Xuewei Chen, Yu Xiong, Lilong Liu, Xi Yuan, Honglin Tang, Chong Shu, Jing Zhang, Austin M. Guo, Honglei Chen, Jing Yang

Supplementary Data from CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer

Funding

National Natural Science Foundation of China (NSFC)

History

ARTICLE ABSTRACT

The identification of a role for CYP4F2-dependent metabolism in driving immune evasion in non–small cell lung cancer reveals a strategy to improve the efficacy of immunotherapy by inhibiting CYP4F2.See related article by Van Ginderachter, p. 3882