Supplementary Data from Autophagy, Cell Viability, and Chemoresistance Are Regulated By miR-489 in Breast Cancer

<p>Figure S1. miR-489 modulates autophagy. Figure S2. Western blot analysis of autophagy flux in breast cancers. Figure S3. Validation of microarray using real-time RT-PCR analysis. Figure S4. miR-489 restoration in HCC1954 and T47D cells under starvation. Figure S5. Endogenous expression level of miR-489 in different classes of breast cancer cell lines. Figure S6. Drug sensitivity assay with cisplatin and doxorubicin. Figure S7. ULK1 restoration rescues MDA-MB-231 cells from cytotoxic effect of miR-489. Figure S8. Characterization and validation of nanoparticles in vitro and in vivo. Figure S9. Correlation of miR-489 and ULK1 mRNA expression in breast cancers. Supplemental Experimental Procedures Supplementary Table 1: Primer list and sequences. Supplementary Table 2: Demographic and histopathology data of the patient samples.</p>