Supplementary Data S1 from The RPL/RPS Gene Signature of Melanoma CTCs Associates with Brain Metastasis

Bowley, Tetiana Y.; Lagutina, Irina V.; Francis, Carol; Sivakumar, Sinduja; Selwyn, Reed G.; Taylor, Erik; Guo, Yan; Fahy, Bridget N.; Tawfik, Bernard; Marchetti, Dario

doi:10.1158/2767-9764.22545534.v1

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Supplementary Data S1 from The RPL/RPS Gene Signature of Melanoma CTCs Associates with Brain Metastasis

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posted on 2023-04-04, 01:44 authored by Tetiana Y. Bowley, Irina V. Lagutina, Carol Francis, Sinduja Sivakumar, Reed G. Selwyn, Erik Taylor, Yan Guo, Bridget N. Fahy, Bernard Tawfik, Dario Marchetti

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HHS | NIH | NCI | National Cancer Institute (NCI)

HHS | NIH | Office of Extramural Research, National Institutes of Health (OER)

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ARTICLE ABSTRACT

This study reports first evidence of RPL/RPS gene signature driving melanoma brain metastasis. Complex multilevel approach was performed to identify MBM signature and confirm its relevance to clinical settings. Novel MRI CTC-derived MBM mouse xenograft was established to monitor MBM spatial and temporal development and progression.

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Biomarkers Cancer risk biomarkers Liquid Biopsy Preclinical Models Animal models of cancer Progression, Invasion & Metastasis Metastasis Skin Cancers Melanoma Precision Medicine Translational Research Tumor Evolution

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Supplementary Data S1 from The RPL/RPS Gene Signature of Melanoma CTCs Associates with Brain Metastasis

Funding

HHS | NIH | NCI | National Cancer Institute (NCI)

HHS | NIH | Office of Extramural Research, National Institutes of Health (OER)

History

ARTICLE ABSTRACT

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