posted on 2023-04-04, 02:22authored byBoris Shorning, Neil Trent, David F. Griffiths, Thomas Worzfeld, Stefan Offermanns, Matthew J. Smalley, Magali Williamson
Metastases in Ptenfl/flKrasG12V mice
Funding
prostate cancer research (charity no. 1156027)
History
ARTICLE ABSTRACT
Few therapeutic targets have been identified specifically for preventing locally invasive/oligometastatic prostate cancer from becoming more widely disseminated. Our findings suggest Plexin-B1 signaling, particularly from the clinically relevant P1597L mutant, is such a target.