Figure S8 from Fibronectin Contributes to a BRAF Inhibitor–driven Invasive Phenotype in Thyroid Cancer through EGR1, Which Can Be Blocked by Inhibition of ERK1/2

Hicks, Hannah M.; Pozdeyev, Nikita; Sams, Sharon B.; Pugazhenthi, Umarani; Bales, Elise S.; Hofmann, Marie-Claude; McKenna, Logan R.; Schweppe, Rebecca E.

doi:10.1158/1541-7786.23516056.v1

Figure S8 from Fibronectin Contributes to a BRAF Inhibitor–driven Invasive Phenotype in Thyroid Cancer through EGR1, Which Can Be Blocked by Inhibition of ERK1/2

journal contribution

posted on 2023-06-14, 15:20 authored by Hannah M. Hicks, Nikita Pozdeyev, Sharon B. Sams, Umarani Pugazhenthi, Elise S. Bales, Marie-Claude Hofmann, Logan R. McKenna, Rebecca E. Schweppe

Figure S8. The effects of EGR1 depletion on signaling responses to BRAF inhibition and invasion.

History

ARTICLE ABSTRACT

Together, these data show that increased invasion represents a new mechanism of resistance to BRAF inhibition in thyroid cancer that can be targeted with an ERK1/2 inhibitor.