American Association for Cancer Research
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Figure S6 from Serum Free Fatty Acid Changes Caused by High Expression of Stearoyl-CoA Desaturase 1 in Tumor Tissues Are Early Diagnostic Markers for Ovarian Cancer

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posted on 2023-09-13, 14:20 authored by Kanoko Katoh, Yuki Katoh, Akiko Kubo, Miho Iida, Yuji Ikeda, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Daiki Kato, Makoto Suematsu, Shuichi Hirai, Kei Kawana

Supplemental figure S6. Effect of short-term diet on serum free fatty acid levels. Serum was collected from healthy donors (n=7) pre and 2 hours post diet, and free fatty acids were measured. Gray lines represent individual values and black lines represent average values. n.s., not significant.

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT)

Takeda Science Foundation (TSF)

The Seiichi Imai Memorial Foundation

The Japan Society of Gynecologic Oncology

Nihon University

MEXT | JST | Moonshot Research and Development Program (Moonshot)

MEXT | JST | Exploratory Research for Advanced Technology (ERATO)

Human Biology Microbiome Quantum Research Center (WPI-Bio2Q)

History

ARTICLE ABSTRACT

Measurement of serum FFA levels by changes in the expression of fatty acid metabolizing enzymes in tumor tissue would allow early detection of ovarian cancer. In particular, the SCD1-associated FFAs, oleic and arachidic acid, would be powerful new screening tools for early-stage ovarian cancer.