American Association for Cancer Research
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Figure S6 from Dissecting the Origin of Heterogeneity in Uterine and Ovarian Carcinosarcomas

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posted on 2023-05-10, 14:20 authored by Anne-Sophie Sertier, Anthony Ferrari, Roxane M. Pommier, Isabelle Treilleux, Sandrine Boyault, Mojgan Devouassoux-Shisheboran, Janice Kielbassa, Emilie Thomas, Laurie Tonon, Vincent Le Texier, Amandine Charreton, Anne-Pierre Morel, Anne Floquet, Florence Joly, Dominique Berton-Rigaud, Gwenaël Ferron, Laurent Arnould, Sabrina Croce, Guillaume Bataillon, Pierre Saintigny, Eliane Mery-Lamarche, Christine Sagan, Aruni P. Senaratne, Ivo G. Gut, Fabien Calvo, Alain Viari, Maria Ouzounova, Isabelle Ray-Coquard, Alain Puisieux

Alteration of genes of TP53, PI3K and cell cycle pathways in uterine and ovarian CS.

Funding

Institut National de la Santé et de la Recherche Médicale (Inserm)

Institut National Du Cancer (INCa)

Agence Nationale de la Recherche (ANR)

History

ARTICLE ABSTRACT

We have provided a detailed characterization of the genomic landscape of CS and identified EMT as a common mechanism associated with phenotypic divergence, linking CS heterogeneity to genetic, transcriptomic, and epigenetic influences.