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Figure S5 from Serum Free Fatty Acid Changes Caused by High Expression of Stearoyl-CoA Desaturase 1 in Tumor Tissues Are Early Diagnostic Markers for Ovarian Cancer

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posted on 2023-09-13, 14:20 authored by Kanoko Katoh, Yuki Katoh, Akiko Kubo, Miho Iida, Yuji Ikeda, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Daiki Kato, Makoto Suematsu, Shuichi Hirai, Kei Kawana

Supplemental figure S5. Correlation between serum free fatty acid levels and BMI in patients with early-stage ovarian cancer. Analysis of the correlation between serum free fatty acid levels and BMI with the ability to diagnose stage I and II ovarian cancer patients, shown in Figure 5A and B.

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT)

Takeda Science Foundation (TSF)

The Seiichi Imai Memorial Foundation

The Japan Society of Gynecologic Oncology

Nihon University

MEXT | JST | Moonshot Research and Development Program (Moonshot)

MEXT | JST | Exploratory Research for Advanced Technology (ERATO)

Human Biology Microbiome Quantum Research Center (WPI-Bio2Q)

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ARTICLE ABSTRACT

Measurement of serum FFA levels by changes in the expression of fatty acid metabolizing enzymes in tumor tissue would allow early detection of ovarian cancer. In particular, the SCD1-associated FFAs, oleic and arachidic acid, would be powerful new screening tools for early-stage ovarian cancer.

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    Cancer Research Communications

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    Keywords

    BiomarkersEarly detection biomarkersSerum biomarkersDiagnostic biomarkersLiquid BiopsyMetabolismMetabolomicsGynecological CancersOvarian cancer

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