American Association for Cancer Research
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Figure S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

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journal contribution
posted on 2023-04-04, 01:46 authored by Alvaro G. Alvarado, Kaleab Tessema, Sree Deepthi Muthukrishnan, Mackenzie Sober, Riki Kawaguchi, Dan R. Laks, Aparna Bhaduri, Vivek Swarup, David A. Nathanson, Daniel H. Geschwind, Steven A. Goldman, Harley I. Kornblum

Gene lists differentially correlate with cell cycle and stemness signatures

Funding

UC President's Postdoctoral Fellowship

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (AMRF)

HHS | NIH | National Cancer Institute (NCI)

History

ARTICLE ABSTRACT

Molecular classification of GBM has not yet resulted in the development of effective therapies. We have developed an integrative approach to identify molecular targets differentially utilized by individual tumors. This approach could lead to patient- and tumor-specific therapeutics.