Figure S4 from Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

Dodson, Anne E.; Shenker, Sol; Sullivan, Pamela; Nayak, Sumeet U.; Middleton, Chris; McGuire, Michael; Chipumuro, Edmond; Mishina, Yuji; Tobin, Erica R.; Cadzow, Louise; Wylie, Andrew A.; Sangurdekar, Dipen

doi:10.1158/2767-9764.27979650

Figure S4 from Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

https://doi.org/10.1158/2767-9764.27979650

journal contribution

posted on 2024-12-06, 09:20 authored by Anne E. Dodson, Sol Shenker, Pamela Sullivan, Sumeet U. Nayak, Chris Middleton, Michael McGuire, Edmond Chipumuro, Yuji Mishina, Erica R. Tobin, Louise Cadzow, Andrew A. Wylie, Dipen Sangurdekar

<p>Characterization of HRDsum scores in cell lines</p>

History

Related Materials

1.
DOI - Is supplement to Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

ARTICLE ABSTRACT

HRD is common in cancer and can be exploited therapeutically, as it sensitizes cells to DNA-damaging agents. Here, we scored more than 1,300 cancer cell lines for HRD using two different bioinformatic approaches, thereby enabling large-scale analyses that provide insights into the etiology and features of HRD.

Usage metrics

Keywords

Artificial Intelligence & Machine Learning Biomarkers Computational Methods Dna Damage Database Resources Dna Damage And Repair In Vitro Models Of Cancer Precision Medicine Preclinical Models Sequence Analysis

Licence

CC BY

Figure S4 from Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

History

Related Materials

ARTICLE ABSTRACT

Usage metrics

Categories

Keywords

Licence

Exports