Fig S7 from World Trade Center Dust Exposure Promotes Cancer in PTEN-deficient Mouse Prostates

Wang, Lin; Xu, Yitian; Zhang, Licheng; Kang, Kyeongah; Kobryn, Andriy; Portman, Kensey; Gordon, Ronald E; Pan, Ping-Ying; Taioli, Emanuela; Aaronson, Stuart A; Chen, Shu-Hsia; Mulholland, David J

doi:10.1158/2767-9764.22544742.v1

Fig S7 from World Trade Center Dust Exposure Promotes Cancer in PTEN-deficient Mouse Prostates

https://doi.org/10.1158/2767-9764.22544742

journal contribution

posted on 2023-04-04, 01:25 authored by Lin Wang, Yitian Xu, Licheng Zhang, Kyeongah Kang, Andriy Kobryn, Kensey Portman, Ronald E Gordon, Ping-Ying Pan, Emanuela Taioli, Stuart A Aaronson, Shu-Hsia Chen, David J Mulholland

<p>Fig. S7. Aggregate tSNE plots generated from aggregate analysis of different clusters of WTC and control patients. A, Circled populations in t-SNE plots showed significant differences between WTC and control patients. B, List of markers used to define the clusters identified in tSNE plots (WTC, n=8 and non-WTC, n=12). C, Meta clusters showing the difference in cell density values occurring in IMC tissue samplings (n=2) for each patient sample (n=10).</p>

Funding

HHS | CDC | National Institute for Occupational Safety and Health (NIOSH)

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DOI - Is supplement to World Trade Center Dust Exposure Promotes Cancer in PTEN-deficient Mouse Prostates

ARTICLE ABSTRACT

We provide the first evidence that exposure to WTC dust promotes prostate cancer progression. These data may impact the diagnoses, clinical management, and treatment of responders who have or will develop cancer.