posted on 2023-06-02, 08:21authored byNicole M. Rossi, Jieqiong Dai, Yi Xie, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Hong Lou, Joseph F. Boland, Meredith Yeager, Roberto Orozco, Enrique Alvirez Freites, Lisa Mirabello, Eduardo Gharzouzi, Michael Dean
Supplementary figures
Funding
National Cancer Institute (NCI)
United States Department of Health and Human Services
Multimers of the HPV genome are generated in cervical tumors replicating as extrachromosomal episomes, which is associated with deletion and rearrangement of the HPV genome and provides a mechanism for oncogenesis without integration.