Supplementary Figures S3 to S6 from Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer
posted on 2023-04-03, 23:07authored byElizabeth Scheid, Pierre Major, Alain Bergeron, Olivera J. Finn, Russell D. Salter, Robin Eady, Bader Yassine-Diab, David Favre, Yoav Peretz, Claire Landry, Sebastien Hotte, Som D. Mukherjee, Gregory A. Dekaban, Corby Fink, Paula J. Foster, Jeffery Gaudet, Jean Gariepy, Rafick-Pierre Sekaly, Louis Lacombe, Yves Fradet, Ronan Foley
Figure S3: Representative gating scheme illustrating the functional subsets induced within the memory CD4+ and CD8+ T cell pools following the stimulation of PBMCs with NP-DCs, KLH-DCs and Tn-MUC1-DCs.; Figure S4: Frequency of KLH-specific cytokine-secreting memory CD4+ T cell subsets and CD8+ T cell subsets at baseline, < 2 months, and > 6 months following vaccination.; Figure S5 Frequency of Tn-MUC1-specific cytokine-secreting memory CD4+ T cell subsets (A) and CD8+ T cell subsets (B) at baseline, < 2 months, and > 6 months following vaccination.; Figure S6: Representative gating scheme illustrating the Treg subsets induced within the CD4+ T cell pool.