Supplementary Figures 1 - 3, Table 1 from Inhibition of NANOG/NANOGP8 Downregulates MCL-1 in Colorectal Cancer Cells and Enhances the Therapeutic Efficacy of BH3 Mimetics
posted on 2023-03-31, 19:02authored byAbid R. Mattoo, Jingyu Zhang, Luis A. Espinoza, J. Milburn Jessup
Figure S1: Dose response curve of CX-1 cells treated with LVshNp81 in combination of increasing concentrations of ABT-737. Supplementary Table 1 : IC50 values of CRC cell lines treated with ABT-737 and ABT-199. Figure S2:Lentiviral Delivered (LV) shRNA to NANOG or NANOGP8 decreases the phosphorylation of AKT and decreases MCL-1 levels. Figure S3: Re-plating assay of CRC cells treated with LV shRNA against NANOG and NANOGP8 and ABT-737.