posted on 2023-03-30, 23:13authored byNuala McCabe, Conor Hanna, Steven M. Walker, David Gonda, Jie Li, Katarina Wikstrom, Kienan I. Savage, Karl T. Butterworth, Clark Chen, D. Paul Harkin, Kevin M. Prise, Richard D. Kennedy
Supplementary Figures 1-4. Figure 1: ATM is a potential drug target for PTEN-deficient cells Figure 2: The synthetic lethality with PTEN loss and ATM inhibition is independent of AKT function Figure 3: The synthetic lethality with PTEN loss and ATM inhibition is independent of RAD51 function Supplementary Figure 4: In vivo efficacy of ATM inhibition with PTEN loss