Supplementary Figure S3 from Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells
posted on 2023-04-03, 17:09authored byPing Fan, Heather E. Cunliffe, Philipp Y. Maximov, Fadeke A. Agboke, Russell E. McDaniel, Xiaojun Zou, Pilar Ramos, Megan L. Russell, V. Craig Jordan
MCF-7:5C cells were treated with vehicle (0.1% DMSO; con), E2 (10-9 mol/L), SP600125 (10-5 mol/L), and E2 (10-9 mol/L) plus SP600125 (10-5 mol/L) for 72 hours. Cells were harvested in TRIzol. Genes were quantitated by real-time RT-PCR. (A) PMAIP1, (B) PPP1R15A. p<0.001, ** compared with control.