posted on 2023-04-04, 02:04authored byWilliam Taylor, Stéphane Deschamps, David Reboutier, Luc Paillard, Agnès Méreau, Yann Audic
endogenous TP63 regulation is unaffected in HaCaT cell lines expressing minigenes
Funding
Ligue Contre le Cancer (French League Against Cancer)
History
ARTICLE ABSTRACT
Quantifying TP63γ isoforms in patients’ tumors could allow for the early detection of patients with HNSCC with an early loss in desmosomal gene expression and poor prognostic. The identification of PTBP1 as a transacting factor controlling TP63γ production may allow to control TP63γ expression.