19406207capr160138-sup-166652_1_supp_3634574_yc7ypv.png (2.08 MB)
Supplementary Figure 6A from Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes
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posted on 2023-04-03, 22:07 authored by Rafael Guerrero-Preston, Blanca L. Valle, Anne Jedlicka, Nitesh Turaga, Oluwasina Folawiyo, Francesca Pirini, Fahcina Lawson, Angelo Vergura, Maartje Noordhuis, Amanda Dziedzic, Gabriela Pérez, Marisa Renehan, Carolina Guerrero-Diaz, Edgar De Jesus Rodríguez, Teresa Diaz-Montes, José Rodríguez Orengo, Keimari Méndez, Josefina Romaguera, Bruce J. Trock, Liliana Florea, David SidranskyBox plots showing the distribution of CpG methylation levels per sample after aligning to HPV16 (S6a) and HPV16-L1 region (S6b). The CpG methylation median in the clinical samples is significantly higher than in the cell lines and higher in urine ccfDNA from the CIN3 than from the CIN1 clinical sample (p<0.05), as expected.